Haemophilus influenzae Non-type b Infection in an Adult Patient with Systemic Lupus Erythematosus

Intern Med. 2020 Dec 1;59(23):3097-3101. doi: 10.2169/internalmedicine.4562-20. Epub 2020 Aug 4.

Abstract

A 40-year-old man with systemic lupus erythematosus taking consecutive oral corticosteroids developed a high-grade fever and disorder of consciousness following acute rhinitis. Haemophilus influenzae type f (Hif) was found and isolated from the blood and cerebrospinal fluid by culture, leading to a diagnosis of meningitis. The prevalence of H. influenzae type b (Hib) infections has decreased due to routine immunization. As a result, the prevalence of invasive non-Hib, including Hif infection, is increasing as a common H. influenzae infection in children and adults. Physicians should be aware of non-Hib H. influenzae infection, even though the Hib vaccine is widely used in Japan.

Keywords: Haemophilus influenzae type f; Hib vaccination; bacterial meningitis; systemic lupus erythematosus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Haemophilus Infections / complications*
  • Haemophilus influenzae type b / immunology
  • Humans
  • Japan
  • Lupus Erythematosus, Systemic / complications*
  • Male