Transarterial Radioembolization for the Treatment of Advanced Hepatocellular Carcinoma Invading the Right Atrium

Cardiovasc Intervent Radiol. 2020 Nov;43(11):1712-1715. doi: 10.1007/s00270-020-02605-3. Epub 2020 Aug 5.


Hepatocellular carcinoma (HCC) has the tendency to invade the portal and/or hepatic venous system. The invasion of the right atrium is uncommonly observed and constitutes a treatment challenge. We report the case of a patient with HCC invading the right atrium treated with 90Yttrium-transarterial radioembolization (90Y-TARE). Following the treatment, organizing pneumonia secondary to nivolumab occurred, raising the question of an interaction between 90Y-TARE and nivolumab.

Keywords: HCC; Immune pneumonitis; Radioembolization.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Hepatocellular / diagnosis
  • Carcinoma, Hepatocellular / therapy*
  • Chemoembolization, Therapeutic / methods*
  • Heart Atria
  • Heart Neoplasms / diagnosis
  • Heart Neoplasms / therapy*
  • Humans
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / therapy*
  • Magnetic Resonance Imaging, Cine / methods
  • Male
  • Neoplasm Invasiveness
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Yttrium Radioisotopes


  • Yttrium Radioisotopes