doi: 10.3390/pathogens9080635.
Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy
Affiliations
- PMID: 32764228
- PMCID: PMC7459993
- DOI: 10.3390/pathogens9080635
Item in Clipboard
Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy
Pathogens.
.
Abstract
We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of NDM-CRE acquisition versus the usual patients (75.9 vs. 25.3 cases/10,000 patient days). The co-infection significantly increased the duration of hospital stay (32.9 vs. 15.8 days).
Keywords: COVID-19; New Delhi metallo-beta-lactamase; health care related infections; surveillance.
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Prevalence of hospitalized COVID-19 patients and incidence of NDM-CRE cases.
Similar articles
-
Trends in hospital acquired New Delhi metallo-beta-lactamase-producing Enterobacterales in Tuscany (Italy) from 2019 to 2021: impact of the COVID-19 pandemic.J Hosp Infect. 2023 Jul;137:44-53. doi: 10.1016/j.jhin.2023.04.016. Epub 2023 May 7. J Hosp Infect. 2023. PMID: 37160231
-
Descriptive analysis of infections due to New Delhi metallo-β-lactamase-producing Enterobacterales in children at Red Cross War Memorial Children's Hospital.S Afr J Infect Dis. 2022 Jul 27;37(1):440. doi: 10.4102/sajid.v37i1.440. eCollection 2022. S Afr J Infect Dis. 2022. PMID: 35935170 Free PMC article.
-
Carbapenem-resistant Klebsiella pneumoniae producing New Delhi metallo-β-lactamase at an acute care hospital, Colorado, 2012.Infect Control Hosp Epidemiol. 2014 Apr;35(4):390-7. doi: 10.1086/675607. Infect Control Hosp Epidemiol. 2014. PMID: 24602944
-
Neonates with Maternal Colonization of Carbapenemase-Producing, Carbapenem-Resistant Enterobacteriaceae: A Mini-Review and a Suggested Guide for Preventing Neonatal Infection.Children (Basel). 2021 May 15;8(5):399. doi: 10.3390/children8050399. Children (Basel). 2021. PMID: 34063374 Free PMC article. Review.
-
Emergence of New Delhi metallo-β-lactamase type 1-producing enterobacteriaceae and non-enterobacteriaceae: global case detection and bacterial surveillance.Int J Infect Dis. 2013 May;17(5):e325-33. doi: 10.1016/j.ijid.2012.11.025. Epub 2013 Jan 16. Int J Infect Dis. 2013. PMID: 23332300 Review.
Cited by
-
Infection with the multidrug-resistant Klebsiella pneumoniae New Delhi metallo-B-lactamase strain in patients with COVID-19: Nec Hercules contra plures?.Front Cell Infect Microbiol. 2024 Apr 16;14:1297312. doi: 10.3389/fcimb.2024.1297312. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38690325 Free PMC article.
-
Device-Associated Infections in COVID-19 Patients: Frequency of Resistant Bacteria, Predictors and Mortality in Medellín, Colombia.Microorganisms. 2024 Mar 22;12(4):640. doi: 10.3390/microorganisms12040640. Microorganisms. 2024. PMID: 38674585 Free PMC article.
-
Antimicrobial Resistance in Qatar: Prevalence and Trends before and Amidst the COVID-19 Pandemic.Antibiotics (Basel). 2024 Feb 21;13(3):203. doi: 10.3390/antibiotics13030203. Antibiotics (Basel). 2024. PMID: 38534638 Free PMC article.
-
Microbiological profile of multidrug resistant bacteria before and during COVID-19 in CHU Mohammed VI.Iran J Microbiol. 2023 Dec;15(6):771-778. doi: 10.18502/ijm.v15i6.14138. Iran J Microbiol. 2023. PMID: 38156298 Free PMC article.
-
Role of Probiotics in Preventing Carbapenem-Resistant Enterobacteriaceae Colonization in the Intensive Care Unit: Risk Factors and Microbiome Analysis Study.Microorganisms. 2023 Dec 12;11(12):2970. doi: 10.3390/microorganisms11122970. Microorganisms. 2023. PMID: 38138114 Free PMC article.
References
-
- Zhou F., Yu T., Du R., Fan G., Liu Y., Liu Z., Xiang J., Wang Y., Song B., Gu X., et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet. 2020;395:1054–1062. doi: 10.1016/S0140-6736(20)30566-3. - DOI - PMC - PubMed
-
- Chen N., Zhou M., Dong X., Qu J., Gong F., Han Y., Qiu Y., Wang J., Liu Y., Wei Y., et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. [(accessed on 10 June 2020)];Lancet. 2020 395:507–513. doi: 10.1016/S0140-6736(20)30211-7. Available online: https://pubmed.ncbi.nlm.nih.gov/32007143/ - DOI - PMC - PubMed
-
- Baggiani A., Briani S., Luchini G., Giraldi M., Martino M.C., Porretta A., Totaro M., Privitera G. Management of healthcare areas for the prevention of COVID-19 emergency in an Italian teaching hospital (Pisa, Tuscany): A hospital renovation plan. Infect. Control Hosp. Epidemiol. 2020:1–6. doi: 10.1017/ice.2020.177. - DOI - PMC - PubMed
-
- Tavoschi L., Forni S., Porretta A., Righi L., Pieralli F., Menichetti F., Falcone M., Gemignani G., Sani S., Vivani P., et al. Prolonged outbreak of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019. [(accessed on 10 June 2020)];Eurosurveillance. 2020 25:2000085. doi: 10.2807/1560-7917.ES.2020.25.6.2000085. Available online: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.6..... - DOI - DOI - PMC - PubMed
-
- European Centre for Disease Prevention and Control Regional outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacteriaceae, Italy, 2018–2019. Stockholm 2019. [(accessed on 10 June 2020)]; Available online: https://www.ecdc.europa.eu/en/publications-data/RRA-new-delhi-metallo-be....
LinkOut - more resources
Full Text Sources
