Contact sensitization in metalworkers: Data from the information network of departments of dermatology (IVDK), 2010-2018

Contact Dermatitis. 2020 Dec;83(6):487-496. doi: 10.1111/cod.13686. Epub 2020 Oct 7.

Abstract

Background: Metalworkers are exposed to a variety of contact allergens by handling tools, metals, metalworking fluids (MWFs), oils and greases, rubber materials, and so on. Most large-scale reports on contact allergy due to MWFs are more than 10-years-old, and there are only few studies on contact allergy in mechanics and other metal workers not exposed to MWFs.

Objectives: To describe a current spectrum of contact sensitization in metalworkers with occupational dermatitis (OD).

Patients and methods: Retrospective analysis of patch test data collected by the Information Network of Departments of Dermatology (IVDK; 2010-2018), stratifying for 804 cutting metalworkers, 2197 mechanics, and 355 other metalworkers.

Results: Cutting metalworkers were most frequently sensitized to monoethanolamine (12.6%), colophonium/abietic acid (11.4%) and formaldehyde releasers (up to 8.5%) from the MWF series, and formaldehyde (4.6%) and iodopropynyl butylcarbamate (4.6%) from the baseline series. Sensitization among mechanics and other metalworkers indicates possible occupational exposure to MWFs, glues, and resins, although this may not be expected from their job titles.

Conclusions: The spectrum of MWF contact allergens remained largely unchanged during the last years. Taking a comprehensive occupational history is indispensable in order to not miss relevant allergen exposures.

Keywords: colophonium; formaldehyde releaser; iodopropynyl butylcarbamate; mechanics; metalworkers; metalworking fluid; monoethanolamine; occupational dermatitis.

MeSH terms

  • Adult
  • Dermatitis, Allergic Contact / diagnosis*
  • Dermatitis, Allergic Contact / etiology
  • Dermatitis, Occupational / diagnosis*
  • Dermatitis, Occupational / etiology
  • Environmental Monitoring / methods
  • Female
  • Germany
  • Hand Dermatoses / chemically induced
  • Hand Dermatoses / diagnosis*
  • Humans
  • Industrial Oils / adverse effects*
  • Male
  • Metallurgy*
  • Middle Aged
  • Occupational Exposure / adverse effects*
  • Patch Tests
  • Retrospective Studies
  • Risk Factors