Interstage Home Monitoring for Infants With Single Ventricle Heart Disease: Education and Management: A Scientific Statement From the American Heart Association

J Am Heart Assoc. 2020 Aug 18;9(16):e014548. doi: 10.1161/JAHA.119.014548. Epub 2020 Aug 11.


This scientific statement summarizes the current state of knowledge related to interstage home monitoring for infants with shunt-dependent single ventricle heart disease. Historically, the interstage period has been defined as the time of discharge from the initial palliative procedure to the time of second stage palliation. High mortality rates during the interstage period led to the implementation of in-home surveillance strategies to detect physiologic changes that may precede hemodynamic decompensation in interstage infants with single ventricle heart disease. Adoption of interstage home monitoring practices has been associated with significantly improved morbidity and mortality. This statement will review in-hospital readiness for discharge, caregiver support and education, healthcare teams and resources, surveillance strategies and practices, national quality improvement efforts, interstage outcomes, and future areas for research. The statement is directed toward pediatric cardiologists, primary care providers, subspecialists, advanced practice providers, nurses, and those caring for infants undergoing staged surgical palliation for single ventricle heart disease.

Keywords: AHA Scientific Statements; cardiovascular abnormalities; caregivers; infant; univentricular heart.

MeSH terms

  • American Heart Association
  • Caregivers / education
  • Checklist
  • Communication
  • Enteral Nutrition*
  • Home Nursing / education
  • Home Nursing / methods*
  • Humans
  • Hypoplastic Left Heart Syndrome / blood
  • Hypoplastic Left Heart Syndrome / nursing*
  • Hypoplastic Left Heart Syndrome / physiopathology
  • Hypoplastic Left Heart Syndrome / surgery
  • Infant
  • Monitoring, Physiologic / methods*
  • Norwood Procedures / methods
  • Oximetry / methods
  • Oxygen / blood*
  • Palliative Care / methods
  • Patient Care Team / organization & administration
  • Patient Discharge / standards
  • Quality Improvement
  • Reoperation
  • Risk Factors
  • Transitional Care / organization & administration
  • Transitional Care / standards
  • United States
  • Weight Gain*


  • Oxygen