Economic and health impacts of infectious diseases in China: A protocol for systematic review and meta analysis

Medicine (Baltimore). 2020 Jul 24;99(30):e21249. doi: 10.1097/MD.0000000000021249.


Background: A worldwide concern has been raised that novel infectious diseases may outbreak rapidly with a limited response time due to globalization. Severe Acute Respiratory Syndrome, influenza A, Avian Influenza Virus, and Corona Virus Disease 2019 are acute respiratory diseases that have been affected by the movements of people, and globalization accelerates these movements. These infectious diseases not only have an overwhelming health impact but also impact the worldwide economy.

Methods: We will conduct a systematic review and meta-analysis in Chinese National Knowledge Infrastructure, WANFANG Database, and the VIP Database for Chinese Technical Periodicals, Web of Science, PubMed, EMBASE, the Cochrane Library, EBSCO host, ProQuest, ProQuest Dissertations & Theses A&I, SAGE Journals, ScienceDirect, JSTOR, and Scopus. We will evaluate the risk of bias of included RCTs according to the criteria and technique proposed in the Cochrane Handbook V.5.1.0 and use ROBINS-I to assess risk of bias in nonrandomized studies. We will use GRADE to evaluate the quality of evidence.

Results: Results of this review will be submitted to a peer-reviewed journal.

Conclusion: To the best of our knowledge, this study will firstly evaluate both health and economic impact of infectious diseases in china and may provide strategy development ideas for future resistance.

MeSH terms

  • Betacoronavirus
  • COVID-19
  • China
  • Communicable Diseases / economics*
  • Coronavirus Infections / economics*
  • Humans
  • Internationality
  • Meta-Analysis as Topic
  • Pandemics / economics*
  • Pneumonia, Viral / economics*
  • SARS-CoV-2
  • Systematic Reviews as Topic