Usefulness of 2-D shear wave elastography for the diagnosis of inguinal lymph node metastasis of malignant melanoma and squamous cell carcinoma

J Dermatol. 2020 Nov;47(11):1312-1316. doi: 10.1111/1346-8138.15545. Epub 2020 Aug 13.

Abstract

We used 2-D shear wave elastography to quantify lymph node hardness, from the shear wave velocity, to determine the presence or absence of metastatic lymphadenopathy in the inguinal lymph nodes of five patients with malignant melanoma and squamous cell carcinoma. The shear wave velocity accurately identified all cases of metastasis confirmed by histology, compared with two false-positive and one false-negative finding with positron emission tomography/computed tomography. 2-D shear wave elastography would be useful to evaluate inguinal lymph node metastasis.

Keywords: 2-D shear wave elastography; lymph node; malignant melanoma; region of interest; squamous cell carcinoma.

MeSH terms

  • Carcinoma, Squamous Cell* / diagnostic imaging
  • Elasticity Imaging Techniques*
  • Humans
  • Lymph Nodes / diagnostic imaging
  • Lymphatic Metastasis / diagnostic imaging
  • Melanoma* / diagnostic imaging