Myxofibrosarcoma, in the calf of a middle aged female: a case report

J Pak Med Assoc. 2020 Aug;70(8):1454-1456. doi: 10.5455/JPMA.36429.


Myxofibrosarcoma belongs to the group of sarcoma tumours, which represent only 1% of the adult tumours worldwide. It is one of the rare, aggressive connective tissue neoplasm of malignant fibrocytes in a myxoid matrix, and mostly occurs in people in their 60s to 80s. Like many other tumours of connective tissue, it reveals high recurrence rates, but rarely metastasise. We present a case of a 50-year-old female who had a large, soft tissue sarcoma over the left leg. Wide surgical excision was done due to its increased size and aggressive clinical behaviour, so as to increase the patient's comfort. On histopathology, the tumour was diagnosed as high-grade myxofibrosarcoma with no evidence of metastasis.

Keywords: Myxofibrosarcoma, local recurrence, metastasis, soft tissue sarcoma..

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fibrosarcoma* / diagnostic imaging
  • Fibrosarcoma* / surgery
  • Humans
  • Leg
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Soft Tissue Neoplasms* / diagnostic imaging
  • Soft Tissue Neoplasms* / surgery