Genome-wide association studies reveal novel loci associated with carcass and body measures in beef cattle

Sayed Haidar Abbas Raza; Samiullah Khan; Motahareh Amjadi; Sameh A Abdelnour; Hussien Ohran; Khalid M Alanazi; Mohamed E Abd El-Hack; Ayman E Taha; Rajwali Khan; Cheng Gong; Nicola M Schreurs; Chunping Zhao; Dawei Wei; Linsen Zan

doi:10.1016/j.abb.2020.108543

Genome-wide association studies reveal novel loci associated with carcass and body measures in beef cattle

Arch Biochem Biophys. 2020 Nov 15:694:108543. doi: 10.1016/j.abb.2020.108543. Epub 2020 Aug 13.

Authors

Affiliations

¹ College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China. Electronic address: haiderraza110@nwafu.edu.cn.
² College of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunnan, 650201, China.
³ Department of Genetics, Eötvös Loránd University, Budapest, Hungary.
⁴ Department of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt.
⁵ Department of Physiology, University of Sarajevo, Veterinary Faculty, Zmajaod Bosne 90, 71000, Sarajevo, Bosnia and Herzegovina.
⁶ Zoology Department, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.
⁷ Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt.
⁸ Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Alexandria University, Edfina, 22578, Egypt.
⁹ College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
¹⁰ Animal Science, School of Agriculture and Environment, Massey University, Palmerston North, New Zealand.
¹¹ School of Agriculture, Ningxia University, Yinchuan, China.
¹² College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China; National Beef Cattle Improvement Center, Northwest A&F University, Yangling, 712100, China. Electronic address: zanlinsen@163.com.

PMID: 32798459
DOI: 10.1016/j.abb.2020.108543

Abstract

Genomic selection has an essential role in the livestock economy by increasing selection productivity. Genomics provides a mechanism to increase the rate of genetic gain using marker-assisted selection. Various quantitative trait loci (QTL) associated with body, carcass and meat quality traits in beef cattle have been found. It is widely accepted that QTL traits in livestock species are regulated by several genes and factors from the environment. Genome-wide association studies (GWAS) are a powerful approach in identifying QTL and to establish genomic regions harboring the genes and polymorphisms associated with specific characteristics in beef cattle. Due to their impact on economic returns, growth, carcass and meat quality traits of cattle are frequently used as essential criteria in selection in breeding programs., GWAS has been used in beef cattle breeding and genetic program and some progress has been made. Furthermore, numerous genes and markers related to productivity traits in beef cattle have been found. This review summarizes the advances in the use of GWAS in beef cattle production and outlines the associations with growth, carcass, and meat quality.

Keywords: Beef cattle; Carcass traits; Genome-wide association; Growth; Meat quality.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Body Weights and Measures*
Cattle
Food Quality
Genes
Genome-Wide Association Study*
Mutation
Quantitative Trait Loci*
Red Meat