1 Royal Cornwall Hospitals NHS Trust, Truro, UK; The University of Exeter Medical School, Exeter, UK; Department of Medicine, University of Perugia, Perugia, Italy.
2 Department of Medicine and Surgery, University of Insubria, Varese, Italy; Department of Medicine and Cardiopulmonary Rehabilitation, Maugeri, Care and Research Institutes, IRCCS Tradate, Varese, Italy.
3 Department of Medicine, University of Perugia, Perugia, Italy. Electronic address: paolo.reboldi@unipg.it.