Mitochondrial calcium transport and permeability transition as rational targets for plant protection

Abstract

The mitochondrial permeability transition (MPT) is a death-inducing mechanism that collapses electrochemical gradients across inner mitochondrial membranes. Several studies in model plants have detailed potential MPT-dependent cell death upon abiotic stress in response to heat shock, ultraviolet radiation, heavy metal toxicity and waterlogging. However, the molecular specifics of the MPT and its possible role on plant cell death remain controversial. This review addresses previous and recent developments on the role(s) of the MPT in plants. Considering these advances, MPT targeting can constitute a plausible strategy to ameliorate cell death in plants upon abiotic stress.

Keywords: ATP synthase; Adenine nucleotide translocase; Calcium overload; Cell death; Mitochondrial permeability transition.