Mesenteric phlebosclerosis complicating colonic cancer treated by endoscopic submucosal dissection

Clin J Gastroenterol. 2020 Dec;13(6):1183-1188. doi: 10.1007/s12328-020-01205-5. Epub 2020 Aug 16.


A 67-year old woman with a history of long-term Chinese herb use was admitted to our institution complaining of abdominal pain. Barium enema disclosed rigidity of throughout the proximal colon and a slightly elevated lesion in the transverse colon. Colonoscopy showed diffuse and bronze mucosa in the proximal colon, which was compatible with mesenteric phlebosclerosis. There was also a reddish, elevated lesion in the transverse colon. Magnifying colonoscopy revealed irregular microsurface and microvessels on the surface of the lesion. Under a diagnosis of intramucosal cancer, the elevated lesion was treated by endoscopic submucosal dissection. Histological examination of the resected specimen showed intramucosal well-differentiated adenocarcinoma, and fibrous thickening of the vascular wall together with collagen deposition in the submucosa. The final diagnosis was an intramucosal cancer occurring in mesenteric phlebosclerosis.

Keywords: Cancer; ESD; Endoscopic submucosal dissection; Mesenteric phlebosclerosis; NBI.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Colonic Neoplasms* / complications
  • Colonic Neoplasms* / surgery
  • Colonoscopy
  • Endoscopic Mucosal Resection* / adverse effects
  • Female
  • Humans
  • Mesentery