Medication Abortion Up to 70 Days of Gestation: ACOG Practice Bulletin, Number 225

Obstet Gynecol. 2020 Oct;136(4):e31-e47. doi: 10.1097/AOG.0000000000004082.


Medication abortion, also referred to as medical abortion, is a safe and effective method of providing abortion. Medication abortion involves the use of medicines rather than uterine aspiration to induce an abortion. The U.S. Food and Drug Administration (FDA)-approved medication abortion regimen includes mifepristone and misoprostol. The purpose of this document is to provide updated evidence-based guidance on the provision of medication abortion up to 70 days (or 10 weeks) of gestation. Information about medication abortion after 70 days of gestation is provided in other ACOG publications ().

Publication types

  • Practice Guideline

MeSH terms

  • Abortifacient Agents / pharmacology
  • Abortion, Induced* / methods
  • Abortion, Induced* / standards
  • Clinical Protocols
  • Female
  • Gestational Age
  • Humans
  • Mifepristone / pharmacology*
  • Misoprostol / pharmacology*
  • Pregnancy
  • Pregnancy Trimester, First / drug effects
  • United States


  • Abortifacient Agents
  • Misoprostol
  • Mifepristone