A Novel KMT2A-ARHGEF12 Fusion Gene Identified in a High-Grade B-cell Lymphoma

Cancer Genet. 2020 Aug:246-247:41-43. doi: 10.1016/j.cancergen.2020.08.003. Epub 2020 Aug 7.
No abstract available

Keywords: ARHGEF12; High-Grade B-cell Lymphoma; KMT2A; KMT2A-ARHGEF12 fusion.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 11 / genetics*
  • Histone-Lysine N-Methyltransferase / genetics*
  • Humans
  • Lymphoma, B-Cell / genetics
  • Lymphoma, B-Cell / pathology*
  • Male
  • Myeloid-Lymphoid Leukemia Protein / genetics*
  • Oncogene Proteins, Fusion / genetics*
  • Prognosis
  • Rho Guanine Nucleotide Exchange Factors / genetics*

Substances

  • ARHGEF12 protein, human
  • KMT2A protein, human
  • Oncogene Proteins, Fusion
  • Rho Guanine Nucleotide Exchange Factors
  • Myeloid-Lymphoid Leukemia Protein
  • Histone-Lysine N-Methyltransferase