Meclizine is an FDA-approved first-generation antihistamine used to alleviate motion sickness. By acting as a non-selective H1 antagonist, meclizine addresses the symptoms associated with motion sickness, including dizziness, nausea, and vomiting. Beyond its role in mitigating motion-related discomfort, meclizine demonstrates central anticholinergic actions, making it an option for managing vertigo symptoms induced by vestibular diseases, notably those affecting the inner ear, such as Mèniére disease.
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