Meclizine

Book
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan.
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Excerpt

Meclizine is an FDA-approved first-generation antihistamine used to alleviate motion sickness. By acting as a non-selective H1 antagonist, meclizine addresses the symptoms associated with motion sickness, including dizziness, nausea, and vomiting. Beyond its role in mitigating motion-related discomfort, meclizine demonstrates central anticholinergic actions, making it an option for managing vertigo symptoms induced by vestibular diseases, notably those affecting the inner ear, such as Mèniére disease.

Publication types

  • Study Guide