Fibrosarcoma

Excerpt

Fibrosarcomas are defined as malignant neoplasms composed of fibroblasts that may have varying amounts of collagen production and a "herringbone" architecture. Depending upon the origin, there are 2 main categories of fibrosarcomas: bone and soft tissue tumors. Adult fibrosarcomas have displayed a declining incidence over the past several decades as the classification of fibrosarcoma continually narrows, and other mesenchymal and non-mesenchymal tumors that mimic fibrosarcomas are more accurately diagnosed. Fibrosarcomas can be subdivided into 2 types: infantile or congenital fibrosarcomas and adult-type fibrosarcomas. Infantile fibrosarcomas rarely metastasize, while adult-type fibrosarcomas are highly malignant.