General methods for analysing repeated measures

Stat Med. 1988 Jan-Feb;7(1-2):29-45. doi: 10.1002/sim.4780070108.


We present an overview of issues and methods for analysing repeated measures of a continuous random variable. We discuss modelling the mean vector and covariance structure, statistical efficiency, regression diagnostics, and discrepancies between longitudinal and cross-sectional methods. We illustrate key points with examples and discuss areas requiring further development.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Humans
  • Longitudinal Studies
  • Middle Aged
  • Models, Biological
  • Respiratory Function Tests*
  • Smoking
  • Statistics as Topic*