Increased cardiovascular death rates in a COVID-19 low prevalence area

J Clin Hypertens (Greenwich). 2020 Oct;22(10):1932-1935. doi: 10.1111/jch.14013. Epub 2020 Aug 20.

Abstract

The province of L'Aquila (Central Italy) was marginally affected by COVID-19 pandemic, but changes in health care seeking behaviors were noticed. The authors retrospectively analyzed de-identified data concerning all-cause and cardiovascular hospitalizations, cardiovascular acute phase treatments, and in-hospital cardiovascular deaths in the province of L'Aquila from January 1 to March 31, in 2020 and 2019. Incidence rate ratios (IRR) comparing 2020 and 2019 for admissions/procedures were calculated through Poisson regression. All-cause and cardiovascular mortality in the examined time windows was also assessed. Less all-cause (IRR 0.85, P < .001) and cardiovascular (IRR 0.73, P < .001) hospitalizations occurred in 2020 than in 2019. Less daily cardiovascular procedures were also performed (IRR: 0.74, P = .009). A disproportionate decrease in the number of procedures was observed in relation to cardiovascular hospitalizations in 2020 (-5.5%, P = .001). Unlike all-cause mortality, more in-hospital cardiovascular deaths occurred in March 2020 compared with March 2019 (+6.8%, P = .048).

Keywords: COVID-19; SARS-CoV-2; cardiovascular death; cardiovascular diseases; cardiovascular hospitalization; cardiovascular procedures.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • COVID-19 / complications*
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology
  • COVID-19 / virology
  • Cardiovascular Diseases / complications
  • Cardiovascular Diseases / mortality*
  • Cardiovascular Surgical Procedures / statistics & numerical data*
  • Cost of Illness
  • Death
  • Female
  • Hospital Mortality / trends*
  • Hospitalization / statistics & numerical data*
  • Humans
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • SARS-CoV-2 / genetics