Multisite Randomized Controlled Trial of Bladder Management in Labor With Epidural Analgesia/Anesthesia

J Obstet Gynecol Neonatal Nurs. 2020 Nov;49(6):564-570. doi: 10.1016/j.jogn.2020.07.005. Epub 2020 Aug 18.

Abstract

Objective: To compare the effects of continuous indwelling catheterization with those of intermittent catheterization during labor with epidural analgesia/anesthesia on mode of birth and incidence of urinary tract infection (UTI) symptoms in the postpartum period.

Design: Randomized clinical trial.

Setting: Labor and delivery units at three metropolitan hospitals in the Western United States.

Participants: Women (N = 252) who were nulliparous with term, singleton pregnancies in labor with epidural analgesia/anesthesia.

Methods: Participants were randomized to indwelling or intermittent (every 2 hours) catheterization groups after the administration of epidural analgesia/anesthesia during labor. One to 2 weeks after discharge, participants were contacted and questioned about symptoms of UTI.

Results: A total of 252 participants were enrolled in the study: 81% (n = 202) gave birth vaginally, and 19% (n = 50) gave birth via cesarean. Between the indwelling and intermittent catheterization groups, demographic characteristics were similar. We found no significant difference in the incidence of cesarean birth between groups (15.6% vs. 22.5%, p = .172). Overall, 3% of participants reported and sought treatment for symptoms of UTI within 2 weeks with no significant difference between groups (p = .929).

Conclusion: We found no differences in mode of birth or symptoms of UTI in women who received indwelling or intermittent catheterization during epidural analgesia/anesthesia. We recommend additional research with objective data for UTI diagnosis and larger samples to study the multiple potential confounding variables associated with cesarean birth after catheterization during epidural analgesia/anesthesia.

Keywords: catheterization; epidural analgesia/anesthesia; labor.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anesthesia, Epidural / adverse effects
  • Anesthesia, Epidural / methods*
  • Anesthesia, Epidural / trends
  • Anesthesia, Obstetrical / adverse effects
  • Anesthesia, Obstetrical / methods
  • Anesthesia, Obstetrical / trends
  • Female
  • Humans
  • Labor, Obstetric*
  • Pain Management / adverse effects*
  • Pain Management / methods
  • Pregnancy
  • Urinary Bladder / injuries
  • Urinary Bladder / physiology*