One-year Outcomes of Congenital Duodenal Obstruction: A Population-based Study

J Pediatr Gastroenterol Nutr. 2021 Feb 1;72(2):239-243. doi: 10.1097/MPG.0000000000002921.


Objectives: Congenital duodenal obstruction (CDO) occurs in 1.2 per 10,000 live births and is frequently associated with other anomalies, most commonly cardiac. The aim of this study was to report important outcomes to 1 year following surgical repair.

Methods: This was a prospective population-based study using the British Association of Paediatric Surgeons Congenital Anomaly Surveillance System. Cases were identified at specialist pediatric surgical centres in the United Kingdom during a 12-month period starting in March 2016. Outcomes were recorded at 1 year following surgical repair.

Results: There were 100 infants with possible follow-up at 1 year and follow-up was achieved in 80 of these (80%) of whom 76 were alive at 1 year. The remainder had been discharged home, although one remained on parenteral nutrition. Five (6.1%) infants underwent repeat surgery for reasons related to CDO and overall 23 (23%) experienced at least 1 central venous catheter-related complication within 1 year. Overall mortality either before repair or within 1 year following surgical repair was 8.4% (95% CI 2.5%-14.4%), no deaths were related to CDO.

Conclusions: One year outcomes for CDO are generally very good with poor outcomes typically related to comorbidities. These data are useful for national benchmarking and parental counselling.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Duodenal Obstruction* / epidemiology
  • Duodenal Obstruction* / etiology
  • Duodenal Obstruction* / surgery
  • Humans
  • Infant
  • Parenteral Nutrition, Total
  • Prospective Studies
  • Reoperation
  • United Kingdom / epidemiology