Objective: To compare epidemic characteristics between severe acute respiratory syndrome (SARS) and coronavirus disease 2019 (COVID-19). Methods: The general information, including epidemiological and clinical data of the confirmed cases during the epidemic period of the two infectious diseases was collected. The data of SARS in Guangzhou was derived from the technical files of Guangzhou Center for Disease Control and Prevention (GZCDC), including the statistical report and brief report of the epidemic situation (from January 2 to May 11, 2003);The data of COVID-19 in Wuhan was derived from the epidemic data published by Wuhan health and Health Committee's official website and other publicly reported documents (from December 9, 2019 to March 11, 2020). Descriptive analysis was used for a comparativeanalysis of the time and age characteristics, the number of cases, basic reproduction number (R0), proportion of medical staff in confirmed cases (%), crude mortality, etc. Results: A total of 1 072 cases of SARS in Guangzhou were included in the study. The incidence ratio of male to female was 1∶1.26. 43 cases of death were reported with a mortality rate of 4.01%. The median age was 36 years old. The proportion of medical staff in the early stage of the epidemic was 29.04% (88 cases). As to COVID-19 in Wuhan, a total of 49 978 cases were included, The incidence ratio of male to female was 1.04∶1. The 2 423 cases of death were reported with a mortality rate of 4.85%. The median age was 56 years old. The proportion of medical staff in the early stage of the epidemic was 30.43% (42 cases). Conclusion: The COVID-19 in Wuhan has the characteristics of high incidence and wide population. However, the epidemic situation is falling rapidly, and the prevention and control strategy needs to be adjusted timely. The prevention and control of nosocomial infection should be addressed in future.
目的： 比较重症急性呼吸综合征（SARS）疫情与新型冠状病毒肺炎（新冠肺炎）疫情流行病学特征。 方法： 收集两种传染病流行期间确诊病例的一般情况、流行病学及临床等相关资料，广州市SARS的资料来源于广州市疾病预防控制中心技术档案，包括疫情统计报表、疫情简报等（纳入分析病例的时间为2003年1月2日至5月11日）；武汉市新冠肺炎来源于武汉市卫生健康委官网公布的疫情资料以及公开发表的文献资料（纳入分析病例的时间为2019年12月9日至2020年3月11日）。对两种传染病流行的时间特征、年龄特征以及发病例数、基本再生指数、医护人员感染比例、粗病死率等进行描述性分析。 结果： 广州市SARS疫情纳入研究病例1 072例，男女发病比为1∶1.26，年龄中位数为35岁；报告死亡43例，病死率为4.01%，年龄中位数为56岁；早期医务人员感染比例为29.04%（88例）。武汉市新冠肺炎纳入研究病例为49 978例，男女发病比为1.04∶1，年龄中位数为56岁；报告死亡2 423例，病死率为4.85%；早期医务人员感染比例为30.43%（42例）。 结论： 武汉市新冠肺炎疫情呈现发病强度高、罹患人群广等特征，但疫情回落迅速，防控策略需适时调整。新发呼吸道传染病需重视院感防控。.
Keywords: COVID-19; Comparative analysis; Epidemic characteristics; Severe acute respiratory syndrome.