[Research progress of non-coding RNA in allergic rhinitis]

C Y Qiu; R X Chen; L Cheng

doi:10.3760/cma.j.cn115330-20190322-00176

[Research progress of non-coding RNA in allergic rhinitis]

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 May 7;55(5):538-542. doi: 10.3760/cma.j.cn115330-20190322-00176.

[Article in Chinese]

Authors

C Y Qiu¹, R X Chen¹, L Cheng²

Affiliations

¹ Department of Otorhinolaryngology, the First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
² Department of Otorhinolaryngology, the First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China; Clinical Allergy Center, the First Affiliated Hospital, Nanjing Medical University, and International Centre for Allergy Research, Nanjing Medical University, Nanjing 210029, China.

PMID: 32842374
DOI: 10.3760/cma.j.cn115330-20190322-00176

Abstract

非编码RNA是一类丰富的RNA，主要包括微小RNA（microRNA，miRNA）、长链非编码RNA（lncRNA）和环状RNA（circRNA）。非编码RNA是基因表达的重要调控因子，参与多种人类疾病的发病机制。近年来，研究发现不同类型的非编码RNA功能各异但又相互关联，共同参与的基因调控网路高度复杂，可能在变应性疾病的发生发展中起关键作用。本文将从microRNA、lncRNA和circRNA三个方面阐述非编码RNA与变应性鼻炎的相关性和研究进展，以及未来可能的研究方向。.

MeSH terms

Biomedical Research / trends
Humans
RNA, Untranslated / genetics
RNA, Untranslated / immunology*
Rhinitis, Allergic* / genetics
Rhinitis, Allergic* / immunology

Substances

RNA, Untranslated

Grants and funding

81800890, 81970862/National Natural Science Foundation of China