Mito-Omics and immune function: Applying novel mitochondrial omic techniques to the context of the aging immune system

Ana R Silverstein; Melanie K Flores; Brendan Miller; Su-Jeong Kim; Kelvin Yen; Hemal H Mehta; Pinchas Cohen

doi:10.1016/j.tma.2020.08.001

Mito-Omics and immune function: Applying novel mitochondrial omic techniques to the context of the aging immune system

Transl Med Aging. 2020:4:132-140. doi: 10.1016/j.tma.2020.08.001. Epub 2020 Aug 21.

Authors

Ana R Silverstein¹, Melanie K Flores¹, Brendan Miller¹, Su-Jeong Kim¹, Kelvin Yen¹, Hemal H Mehta¹, Pinchas Cohen¹

Affiliation

¹ Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.

Abstract

Recent advancements in genomic, transcriptomic, proteomic, and metabolomic techniques have prompted fresh inquiry in the field of aging. Here, we outline the application of these techniques in the context of the mitochondrial genome and suggest their potential for use in exploring the biological mechanisms of the aging immune system.

Keywords: Genomics; Immune function; Mitochondria; Proteomics; Transcriptomics.

Abstract

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