An Improved Scoring System Based on Platelet-Albumin-Bilirubin in Predicting Posthepatectomy Liver Failure Outcomes

Dig Dis. 2021;39(3):258-265. doi: 10.1159/000511138. Epub 2020 Aug 26.

Abstract

Background: Posthepatectomy liver failure (PHLF) is one of the major complications of liver resection that causes perioperative mortality. Accurate preoperative assessment of PHLF is of great significance to reduce the complication rate after hepatectomy and improve the survival rate.

Methods: A retrospective study of patients who received hepatectomy from January 2016 to October 2019 at Tang Du Hospital was performed. The area under the receiver operating characteristic (ROC) curve was used to compare the predictive effects of various scoring models on PHLF.

Results: The area under the ROC curve of platelet-albumin-bilirubin (PALBI) score, new platelet-albumin-bilirubin (I-PALBI) score, ALBI score, and MELD score was, respectively, 0.647, 0.772, 0.677, and 0.686 (p < 0.01). The I-PALBI score was significantly better than the other scores.

Conclusions: I-PALBI score can be used as a predictive score of PHLF, and its prediction accuracy is better than other scoring systems.

Keywords: Albumin-bilirubin score; Liver function; Platelet-albumin-bilirubin score; Portal hypertension; Posthepatectomy liver failure.

MeSH terms

  • Albumins / metabolism*
  • Bilirubin / metabolism*
  • Blood Platelets / pathology
  • Female
  • Hepatectomy*
  • Humans
  • Liver Failure / blood*
  • Liver Failure / etiology
  • Liver Failure / surgery*
  • Male
  • Middle Aged
  • Prognosis
  • ROC Curve
  • Retrospective Studies
  • Survival Rate
  • Treatment Outcome

Substances

  • Albumins
  • Bilirubin