Chemical composition of Blumea balsamifera and Magnolia sieboldii essential oils and prevention of UV-B radiation-induced skin photoaging

Nat Prod Res. 2021 Dec;35(24):5977-5980. doi: 10.1080/14786419.2020.1809401. Epub 2020 Aug 28.


Blumea balsamifera essential oils (BBEOs) and Magnolia sieboldii essential oils (MSEOs) have exhibited outstanding antioxidant, anti-bacterial and anti-inflammatory activities. However, their anti-photoaging ability is still unclear. In this study, the chemical compositions of BBEOs and MSEOs are firstly determined by GC-MS analysis, and then their anti-photoaging is evaluated via an ultraviolet radiation (UV-B) induced mice skin-injury model. A total of 35 and 33 components are identified from BBEOs and MSEOs, and their dominant compositions are caryophyllene (18.54%) and borneol (18.33%) in BBEOs, and β-elemene (29.10%), γ-terpinene (17.01%) and (E)-β-ocymene (11.69%) in MSEOs. According to the skin injury model, the application of BBEOs and MSEOs to mice skin can effectively inhibit skin photoaging by down-regulating the expression of inflammatory factors including TNF-α, IL-6 and IL-10. Clearly, both essential oils reveal the potential as additives in cosmetics for anti-photoaging.

Keywords: Blumea balsamifera; Magnolia sieboldii; anti-inflammatory; essential oil; skin photoaging.

MeSH terms

  • Animals
  • Asteraceae*
  • Magnolia*
  • Mice
  • Oils, Volatile* / pharmacology
  • Skin Aging*
  • Ultraviolet Rays


  • Oils, Volatile