Use of mouthwashes against COVID-19 in dentistry

Br J Oral Maxillofac Surg. 2020 Oct;58(8):924-927. doi: 10.1016/j.bjoms.2020.08.016. Epub 2020 Aug 15.


The proximity to the patient during dental care, high generation of aerosols, and the identification of SARS-CoV-2 in saliva have suggested the oral cavity as a potential reservoir for COVID-19 transmission. Mouthwashes are widely-used solutions due to their ability to reduce the number of microorganisms in the oral cavity. Although there is still no clinical evidence that they can prevent the transmission of SARS-CoV-2, preoperative antimicrobial mouth rinses with chlorhexidine gluconate (CHX), cetylpyridinium chloride (CPC), povidone-iodine (PVP-I), and hydrogen peroxide (H2O2) have been recommended to reduce the number of microorganisms in aerosols and drops during oral procedures. This paper therefore aims to provide a comprehensive review of the current recommendations on the use of mouthwashes against the COVID-19 pandemic and to analyse the advantages and disadvantages of most conventional antiseptic mouthwashes used in dentistry.

Keywords: COVID-19; Coronavirus; Dentistry; Mouthwashes; Oral health.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents, Local*
  • Betacoronavirus
  • COVID-19
  • Chlorhexidine
  • Coronavirus Infections*
  • Dentistry
  • Humans
  • Hydrogen Peroxide
  • Mouthwashes*
  • Pandemics*
  • Pneumonia, Viral*
  • SARS-CoV-2


  • Anti-Infective Agents, Local
  • Mouthwashes
  • Hydrogen Peroxide
  • Chlorhexidine