Incidence of Malformations After Early Pregnancy Exposure to Modafinil in Sweden and Norway

JAMA. 2020 Sep 1;324(9):895-897. doi: 10.1001/jama.2020.9840.

Abstract

This pharmacoepidemiology study uses Scandinavian birth registry data to estimate the association between modafinil use during early pregnancy and major congenital malformations among infants born in Norway and Sweden between 2005-2006 and 2016-2017.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Drug-Induced / epidemiology*
  • Abnormalities, Drug-Induced / etiology
  • Adult
  • Central Nervous System Stimulants / adverse effects*
  • Cohort Studies
  • Female
  • Humans
  • Incidence
  • Modafinil / adverse effects*
  • Norway / epidemiology
  • Odds Ratio
  • Pregnancy
  • Pregnancy Trimester, First
  • Registries
  • Sweden / epidemiology

Substances

  • Central Nervous System Stimulants
  • Modafinil