Relationship between contraceptive methods and human papillomavirus positivity

Arch Gynecol Obstet. 2020 Dec;302(6):1407-1412. doi: 10.1007/s00404-020-05754-5. Epub 2020 Sep 3.

Abstract

Purpose: Understanding the effect of contraceptive use on high-risk human papillomavirus (HPV) positivity may provide information that is valuable to women in contraceptive decision-making. This study includes women aged 30-65 years who admitted to Family Planing outpatient clinic and have hrHPVDNA positivity.

Methods: We included a total of 801 women. All participants underwent national cervical cancer screening using HPV screening test conducted by the Cancer Control Department of the Ministry of Health. They completed a questionnaire on demographic information and potential risk factors.

Results: The HPV DNA positivity rate among all participants was 8.4%. The two most common HPV genotypes were HPV16 and HPV51. Meanwhile, hrHPV infection was associated with age, marital status, smoking status, and contraceptive method.

Conclusion: HPV is the most common cause of sexually transmitted diseases. Understanding about the reproductive and demographic characteristics affecting HPV persistence is crucial. The effect of contraceptive methods on HPV positivity is important information that is necessary to be relayed to women by healthcare professionals.

Keywords: Active smoking; Contraceptive method; Human papillomavirus; Intrauterine device.

MeSH terms

  • Adult
  • Aged
  • Contraception / adverse effects*
  • Contraception / methods
  • DNA, Viral / analysis
  • Early Detection of Cancer
  • Female
  • Human papillomavirus 16 / genetics
  • Humans
  • Middle Aged
  • Papillomaviridae / genetics*
  • Papillomavirus Infections / genetics
  • Papillomavirus Infections / virology
  • Retrospective Studies
  • Risk Factors
  • Uterine Cervical Neoplasms / diagnosis*
  • Uterine Cervical Neoplasms / virology

Substances

  • DNA, Viral