Systemic Botulism Toxicity Caused by Pyloric Botox Injection to Treat Gastroparesis

Gordon P Bensen; Cristina C Rutherford; Timothy B Gardner

doi:10.1159/000508854

Systemic Botulism Toxicity Caused by Pyloric Botox Injection to Treat Gastroparesis

Case Rep Gastroenterol. 2020 Jul 28;14(2):373-376. doi: 10.1159/000508854. eCollection 2020 May-Aug.

Authors

Gordon P Bensen¹, Cristina C Rutherford¹, Timothy B Gardner¹

Affiliation

¹ Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.

Abstract

Systemic botulism resulting from therapeutic Botox (OnabotulinumtoxinA) injection has been rarely reported, and never in the context of pylorus injection to treat gastroparesis. We report the case of a 27-year-old female with Emery-Dreifuss muscular dystrophy who developed severe systemic botulism toxicity following the intrapyloric injection of 100 units of Botox to treat gastroparesis. The patient eventually made a full recovery.

Keywords: Botox; Botulism; Complication; Gastroparesis; Toxicity.

Publication types

Case Reports