A Possible Case of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Newborn With Positive Placental In Situ Hybridization of SARS-CoV-2 RNA

Ihab Alamar; Mohammad H Abu-Arja; Taryn Heyman; Drucilla J Roberts; Niyati Desai; Pramod Narula; Beata Dygulska

doi:10.1093/jpids/piaa109

A Possible Case of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Newborn With Positive Placental In Situ Hybridization of SARS-CoV-2 RNA

J Pediatric Infect Dis Soc. 2020 Nov 10;9(5):636-639. doi: 10.1093/jpids/piaa109.

Authors

Ihab Alamar¹, Mohammad H Abu-Arja¹, Taryn Heyman², Drucilla J Roberts³, Niyati Desai⁴, Pramod Narula¹, Beata Dygulska¹

Affiliations

¹ Department of Pediatrics, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York, USA.
² Department of Obstetrics and Gynecology, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York, USA.
³ Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
⁴ Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

Abstract

Little is known about the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the coronavirus disease 2019 (COVID-19) on pregnant mothers and their infants. Moreover, there is no definitive evidence that SARS CoV- 2 can be vertically transmitted from an infected mother to the unborn fetus.

Keywords: COVID-19; SARS-CoV-2; pregnancy; vertical transmission.

© The Author(s) 2020. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Publication types

Case Reports

MeSH terms

Betacoronavirus / genetics
Betacoronavirus / isolation & purification*
COVID-19
Coronavirus Infections / transmission*
Female
Humans
In Situ Hybridization
Infant, Newborn
Infectious Disease Transmission, Vertical*
Nasopharynx / virology
Pandemics
Placenta / virology*
Pneumonia, Viral / transmission*
Pregnancy
Pregnancy Complications, Infectious*
Retrospective Studies
SARS-CoV-2