Oral Manifestations of Systemic Diseases

Dermatol Clin. 2020 Oct;38(4):495-505. doi: 10.1016/j.det.2020.05.010. Epub 2020 Aug 11.

Abstract

Signs and symptoms representative of a systemic condition can manifest in the oral cavity and orofacial region. Such conditions may be previously diagnosed, or the orofacial manifestation may be the presenting sign of an acute or chronic systemic condition not previously diagnosed. Pathologic processes in the mouth, jaws, and contiguous structures could have a direct and indirect impact on the patient's overall systemic condition. Moreover, systemic conditions may result in compromised function of the orofacial region or impact patients' oral health profile. This article reviews selected systemic conditions that present or impact on the oral cavity and orofacial region.

Keywords: Cancer; Oral ulcers; Sjogren’s syndrome; Systemic; Xerostomia.

Publication types

  • Review

MeSH terms

  • Autoimmune Diseases / complications
  • Bacterial Infections / complications
  • Endocrine System Diseases / complications
  • Gastrointestinal Diseases / complications
  • Hematologic Diseases / complications
  • Humans
  • Malnutrition / complications
  • Mouth Diseases / etiology*
  • Mycoses / complications
  • Nervous System Diseases / complications
  • Virus Diseases / complications