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. 2020 Sep 9;181(3):379-381.
doi: 10.1001/jamainternmed.2020.5313. Online ahead of print.

Clinical Outcomes in Young US Adults Hospitalized With COVID-19

Jonathan W Cunningham  1 , Muthiah Vaduganathan  1 , Brian L Claggett  1 , Karola S Jering  1 , Ankeet S Bhatt  1 , Ning Rosenthal  2 , Scott D Solomon  1
Affiliations

Clinical Outcomes in Young US Adults Hospitalized With COVID-19

Jonathan W Cunningham et al. JAMA Intern Med. .

Abstract

This case series examines the clinical outcomes for young adults hospitalized with COVID-19.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Cunningham reported grants from the National Heart, Lung, and Blood Institute (T32HL094301) during the conduct of the study. Dr Vaduganathan reported grants from Harvard Catalyst, grants and personal fees from Amgen, and personal fees from AstraZeneca, Baxter HealthCare, Bayer AG, Boehringer Ingelheim, Cytokinetics, and Relypsa outside the submitted work. Dr Claggett reported personal fees from Amgen, Boehringer Ingelheim, Corvia, MyoKardia, and Novartis outside the submitted work. Dr Rosenthal is an employee of Premier Inc, which curates the Premier Healthcare Database. Dr Bhatt reported speaking fees from Sanofi Pasteur and is supported by the Heart, Lung, and Blood Institute T32 postdoctoral training grant T32HL007604. Dr Solomon reported grants from Alnylam, Amgen, AstraZeneca, Bellerophon, Bayer, BMS, Celladon, Cytokinetics, Eidos, Gilead, GSK, Ionis, Lone Star Heart, Mesoblast, MyoKardia, Neurotronik, National Institutes of Health/National Heart, Lung, and Blood Institute, Novartis, Respicardia, Sanofi Pasteur, Theracos and personal fees from Akros, Alnylam, Amgen, Arena, AstraZeneca, Bayer, BMS, Cardior, Cardurion, Corvia, Cytokinetics, Daiichi-Sankyo, Gilead, GSK, Ironwood, Merck, Myokardia, Novartis, Roche, Takeda, Theracos, Quantum Genetics, Cardurion, AoBiome, Janssen, Cardiac Dimensions, Sanofi-Pasteur, Tenaya, Dinaqor, Tremeau, CellProThera, and Moderna outside the submitted work. No other disclosures were reported.

Figures

Figure.
Figure.. Death and Mechanical Ventilation in Young Adults With and Without Morbid Obesity, Hypertension, and Diabetes
Morbid obesity, diabetes, and hypertension were determined by International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) codes during coronavirus disease 2019 (COVID-19) admission. Proportions of patients experiencing death and mechanical ventilation were compared with a reference group of 8862 middle-aged (age 35-64 years) nonpregnant patients with COVID-19 with none of these conditions in the Premier database (dotted lines). Error bars refer to 95% CIs.
See this image and copyright information in PMC

Comment in

  • doi: 10.1001/jamainternmed.2020.5415

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