Fox-Fordyce Disease: Dermoscopic Perspective

Skin Appendage Disord. 2020 Jul;6(4):247-249. doi: 10.1159/000508201. Epub 2020 Jun 9.


Fox-Fordyce disease (FFD) is a rare chronic skin disease of the apocrine unit. It presents chiefly in postpubertal females as grouped, monomorphic, skin-colored follicular papules associated with intense pruritus commonly in axillae but may involve pubic, perineal, areolar, and umbilical areas [An Bras Dermatol. 2018;93(1):161-2]. Diagnosis is mostly clinical as histological features are often nonspecific and variable. However, the lesions at times may be mistaken for irritant contact dermatitis, lichen nitidus, syringoma, etc. [J Dermatol. 2009;36(9):485-90]. Dermoscopy is being increasingly utilized in pigmentary and inflammatory skin disorders. In this communication, we describe the dermoscopic features in FFD, which shows typical light brown to dark brown folliculocentric structureless areas with loss of dermatoglyphics. Some of the lesions also show hyperkeratotic follicular plugging.

Keywords: Axilla; Dermoscopy; Fox-Fordyce disease; Sweat glands; USB dermatoscope.

Publication types

  • Case Reports