Liver in the limelight in the corona (COVID-19) time

World J Clin Cases. 2020 Aug 26;8(16):3405-3410. doi: 10.12998/wjcc.v8.i16.3405.

Abstract

The novel coronavirus, severe acute respiratory syndrome-corona virus-2 (SARS-CoV-2), is a topic of great interest currently in the medical field due to the significant morbidity and mortality associated with it. There is immense curiosity about this virus as knowledge about it is limited from pathogenesis, host related factors and the variable effect it has on different patient populations. Though it has claimed fame due to its ability to compromise the respiratory system, it possess the capability to infect other organs as well including the liver. It is important for clinicians to recognize that the virus can result in multi-organ dysfunction as well. Presentation with gastrointestinal symptoms and involvement of the liver can be subtle and can be misdiagnosed. Those with pre-existing liver disease may be more susceptible as well as those who are immunosuppressed or have other co-morbidities. This review article provides a brief overview of some of the information that is available so far with regards to how the liver is impacted by the coronavirus.

Keywords: Angiotensin converting enzyme 2 enzyme; COVID-19; Coronavirus; Gastrointestinal; Liver; SARS-CoV-2.

Publication types

  • Review