Local failure after definitive radiation treatment of lymph-node positive prostate cancer: supporting the use of novel imaging techniques to personalize treatment options

Avinash R Chaurasia; Clayton P Smith; Peter Pinto; Bradford Wood; Erica Schott; Theresa Cooley-Zgela; Ravi Madan; Liza Lindenberg; Esther Mena; Peter Choyke; Deborah Citrin; Baris Turkbey

doi:10.1259/bjrcr.20200001

Local failure after definitive radiation treatment of lymph-node positive prostate cancer: supporting the use of novel imaging techniques to personalize treatment options

BJR Case Rep. 2020 Apr 17;6(3):20200001. doi: 10.1259/bjrcr.20200001. eCollection 2020 Sep 1.

Authors

Affiliations

¹ Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
² Georgetown University School of Medicine, Washington, DC, USA.
³ Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
⁴ Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
⁵ Genitourinary Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
⁶ Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

Abstract

Patients with lymph-node positive prostate cancer are often treated with external beam radiotherapy with androgen deprivation therapy¹, but are expected to have a high rate of biochemical failure. Recently, MRI and molecular imaging have afforded the opportunity to elucidate otherwise occult sites of recurrence after conventional imaging. We present an unusual case of local failure within the prostate after definitive radiation treatment of lymph-node positive prostate cancer, in which advanced imaging allowed for a potentially curative salvage treatment option.

Publication types

Case Reports