Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review

Biosensors (Basel). 2020 Sep 10;10(9):121. doi: 10.3390/bios10090121.


Over recent three decades, the electrochemical techniques have become widely used in biological identification and detection, because it presents optimum features for efficient and sensitive molecular detection of organic compounds, being able to trace quantities with a minimum of reagents and sample manipulation. Given these special features, electrochemical techniques are regularly exploited in disease diagnosis and monitoring. Specifically, amperometric electrochemical analysis has proven to be quite suitable for the detection of physiological biomarkers in monitoring health conditions, as well as toward the control of reactive oxygen species released in the course of oxidative burst during inflammatory events. Besides, electrochemical detection techniques involve a simple and swift assessment that provides a low detection-limit for most of the molecules enclosed biological fluids and related to non-transmittable morbidities.

Keywords: antioxidants; ascorbic acid; dopamine; electrochemistry; hydrogen peroxide; non-communicable diseases; reactive oxygen species; uric acid.

Publication types

  • Systematic Review

MeSH terms

  • Biosensing Techniques*
  • Electrochemical Techniques*
  • Humans
  • Noncommunicable Diseases / epidemiology*