Utilization of video oculography to quantify oculomotor dysfunction in anti-DPPX encephalitis: A case study

Mult Scler Relat Disord. 2020 Nov:46:102460. doi: 10.1016/j.msard.2020.102460. Epub 2020 Aug 29.

Abstract

Anti-DPPX encephalitis is an increasingly recognized cause of neurological disability. We describe a case of a 44 year-old woman who presented to our facility with the chief complaint of confusion, weight loss, and a visual disturbance. Multidirectional nystagmus was noted, and she underwent additional evaluation. Anti-DPPX antibodies returned positive, and she treated with immunotherapy with improvement in her symptoms and deficits. We describe the video-oculography findings in the case, and discuss the implications for localization.

Keywords: DPPX; Encephalitis; Oculography; Oculomotor.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Encephalitis*
  • Eye Movements
  • Female
  • Humans
  • Immunotherapy