Metagenomic 16S rDNA amplicon datasets from adolescents with normal weight, obesity, and obesity with irritable bowel syndrome from Eastern Siberia, Russia

Natalia Belkova; Elizaveta Klimenko; Anastasiya Romanitsa; Anna Pogodina; Lubov Rychkova

doi:10.1016/j.dib.2020.106141

Metagenomic 16S rDNA amplicon datasets from adolescents with normal weight, obesity, and obesity with irritable bowel syndrome from Eastern Siberia, Russia

Data Brief. 2020 Aug 6:32:106141. doi: 10.1016/j.dib.2020.106141. eCollection 2020 Oct.

Authors

Natalia Belkova¹, Elizaveta Klimenko¹, Anastasiya Romanitsa¹, Anna Pogodina¹, Lubov Rychkova¹

Affiliation

¹ Scientific Centre for Family Health and Human Reproduction Problems, 16, Timiryazeva Street, Irkutsk 664003, Russia.

Abstract

Childhood obesity and its consequences are a significant public health problem worldwide. Gut microbiota has a potential role in the development of. In the current datasets, we present 16S rDNA amplicon metasequencing of the gut microbiome of adolescents with normal weight, obesity, and obesity with irritable bowel syndrome (IBS) carried out using the Illumine platform. The datasets presented in this report are partly shown in the research article named "Composition and Structure of Gut Microbiome in Adolescents with Obesity and Different Breastfeeding Duration" [1]. The amplicon metasequencing data were deposited at NCBI SRA as BioProject PRJNA604466. A total of 22 phyla, 34 classes, and 231 genera were revealed. Three groups of adolescents had 196 core amplicon sequence variant (ASV), whereas 45, 24, and 1 ASV were unique for adolescents with normal body weight, obesity, and obesity with IBS, respectively. The metagenomic data were first obtained for adolescents from Eastern Siberian, Russia. They have the potential for predictive analysis, which is crucial for understanding microbial community dynamics and their role in the development of the intestinal microbiome. Considering the recent focus on gut microbiota, new datasets are needed to determine the association between gut microbes and the weight of adolescents from previously unexplored regions such as Siberia, Russia.

Keywords: Adolescents; Amplicon metasequencing; Human gut microbiome; Irritable bowel syndrome; Normal weight; Obesity.