Hyperprogression of a Sinonasal Squamous Cell Carcinoma Following Programmed Cell Death Protein-1 Checkpoint Blockade

JAMA Otolaryngol Head Neck Surg. 2020 Dec 1;146(12):1176-1178. doi: 10.1001/jamaoto.2020.2584.

Authors

Said Izreig¹, Faisal Alzahrani^{1

2}, Joseph Earles^{1

3}, Saral Mehra^{1

3}, Benjamin L Judson^{1

3}, Zenggang Pan⁴, Rahmatullah W Rahmati^{1

3}

Affiliations

¹ Division of Otolaryngology, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut.
² King Saud University, Riyadh, Saudi Arabia.
³ Yale Cancer Center, New Haven, Connecticut.
⁴ Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.

PMID: 32940637
DOI: 10.1001/jamaoto.2020.2584

No abstract available

Publication types

Case Reports

MeSH terms

Antibodies, Monoclonal, Humanized / adverse effects*
Antineoplastic Agents, Immunological / adverse effects*
Carcinoma, Squamous Cell / drug therapy*
Carcinoma, Squamous Cell / pathology*
Carcinoma, Squamous Cell / surgery
Disease Progression
Humans
Male
Maxillary Sinus Neoplasms / drug therapy*
Maxillary Sinus Neoplasms / pathology*
Maxillary Sinus Neoplasms / surgery
Middle Aged
Tumor Burden

Substances

Antibodies, Monoclonal, Humanized
Antineoplastic Agents, Immunological
pembrolizumab