Vasopressin Neurons: Master Integrators of Time and Homeostasis

Ivana L Bussi; Raymond E A Sanchez; Horacio O de la Iglesia

doi:10.1016/j.tins.2020.08.007

Vasopressin Neurons: Master Integrators of Time and Homeostasis

Trends Neurosci. 2020 Nov;43(11):839-841. doi: 10.1016/j.tins.2020.08.007. Epub 2020 Sep 15.

Authors

Ivana L Bussi¹, Raymond E A Sanchez¹, Horacio O de la Iglesia²

Affiliations

¹ Department of Biology and Graduate Program in Neuroscience, University of Washington, Seattle, WA 98195-1800, USA.
² Department of Biology and Graduate Program in Neuroscience, University of Washington, Seattle, WA 98195-1800, USA. Electronic address: horaciod@uw.edu.

PMID: 32948352
DOI: 10.1016/j.tins.2020.08.007

Abstract

A recent article by Gizowski and Bourque shows that vasopressinergic (VP) neurons within the suprachiasmatic nucleus (SCN) master circadian clock have the ability of encoding afferent input from osmosensors and generating appropriate homeostatic responses, suggesting that SCN neurons can integrate internal circadian time and acute changes in homeostatic markers.

Keywords: circadian; internal sensors; internal time; osmosensing; suprachiasmatic nucleus.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Circadian Rhythm*
Homeostasis
Neurons / metabolism
Suprachiasmatic Nucleus
Synaptic Transmission
Thirst*
Vasopressins / metabolism

Substances

Vasopressins

Grants and funding

R01 NS110012/NS/NINDS NIH HHS/United States