The differential effects of meclofenoxate on memory loss in the elderly

Age Ageing. 1977 May;6(2):123-31. doi: 10.1093/ageing/6.2.123.


A double-blind study of the effects of meclofenoxate on memory performance of fit, able, elderly subjects was carried out. A number of performance measures, designed to measure various aspects of memory function were employed. These revealed that meclofenoxate appears to increase the consolidation of new information into long-term memory, but does not affect other aspects of remembering. It was also found that significantly more of the subjects receiving meclofenoxate reported an increased level of mental alertness.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Female
  • Glycolates / therapeutic use*
  • Humans
  • Male
  • Meclofenoxate / therapeutic use*
  • Memory / drug effects
  • Memory Disorders / drug therapy*
  • Memory, Short-Term / drug effects
  • Placebos


  • Glycolates
  • Placebos
  • Meclofenoxate