Spinal anaplastic ganglioglioma

Br J Neurosurg. 2023 Oct;37(5):1186-1189. doi: 10.1080/02688697.2020.1823936. Epub 2020 Sep 24.

Abstract

Anaplastic gangliogliomas of the spinal cord are extremely rare with only four cases reported in the literature. Here we present the case of a 22-year-old female who presented acutely with quadraparesis and urinary retention. Radiographic imaging demonstrated an intramedullary lesion within the cervical spine. She underwent a cervical laminectomy and resection of the lesion under neurophysiological monitoring. Post-operatively, she regained some function, but remained paraparetic. Histopathology demonstrated an anaplastic ganglioglioma (WHO Grade 3). She subsequently underwent radiotherapy. Following surgery, she remained stable and had MRC Grade 3 Power in all four limbs. Herein, we describe a previously undescribed case of cervical anaplastic ganglioglioma and review the existing literature.

Keywords: Spinal tumour; chemotherapy; ganglioglioma; laminectomy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms* / surgery
  • Central Nervous System Neoplasms*
  • Female
  • Ganglioglioma* / diagnostic imaging
  • Ganglioglioma* / pathology
  • Ganglioglioma* / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Radiography
  • Spinal Cord Neoplasms* / diagnostic imaging
  • Spinal Cord Neoplasms* / pathology
  • Spinal Cord Neoplasms* / surgery
  • Young Adult