Characterization of 2 Neisseria gonorrhoeae Strains With High-Level Azithromycin Resistance Isolated in 2015 and 2018 in Japan

Sex Transm Dis. 2021 Jul 1;48(7):e85-e87. doi: 10.1097/OLQ.0000000000001303.

Abstract

We identified and characterized the first 2 Neisseria gonorrhoeae strains with high-level azithromycin resistance isolated in Japan. These were in the clade of ceftriaxone- and azithromycin-resistant strains isolated in Australia and the United Kingdom. The multilocus sequence typing, N. gonorrhoeae multiantigen sequence typing, and N. gonorrhoeae sequence typing for antimicrobial resistance types of these strains were found in gonococci from eastern Asia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Australia
  • Azithromycin / pharmacology
  • Ceftriaxone / pharmacology
  • Drug Resistance, Bacterial / genetics
  • Gonorrhea* / drug therapy
  • Gonorrhea* / epidemiology
  • Humans
  • Japan / epidemiology
  • Microbial Sensitivity Tests
  • Neisseria gonorrhoeae* / genetics

Substances

  • Anti-Bacterial Agents
  • Ceftriaxone
  • Azithromycin