COVID-19 randomized controlled trials in medRxiv and PubMed

Eur J Intern Med. 2020 Nov:81:97-99. doi: 10.1016/j.ejim.2020.09.019. Epub 2020 Sep 22.

¹ Hospital Care Research Unit, Hyogo Prefectural Amagasaki General Medical Center, Higashinaniwa-cho 2-17-77, Amagasaki 660-8550 Japan; Department of Community Medicine in the Graduate School of Medicine, Kyoto University, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan; Systematic Review Workshop Peer Support Group (SRWS-PSG), Japan; Department of Respiratory Medicine, Hyogo Prefectural Amagasaki General Medical Center, Higashinaniwa-cho 2-17-77, Amagasaki 660-8550 Japan. Electronic address: youkiti@gmail.com.
² Systematic Review Workshop Peer Support Group (SRWS-PSG), Japan; Department of Gynecology, Women's Center, Yotsuya Medical Cube, 7-7, Nibancho, Chiyoda-ku, Tokyo 102-0084, Japan.
³ Systematic Review Workshop Peer Support Group (SRWS-PSG), Japan; Department of Physical Therapy, School of Health Sciences at Fukuoka, International University of Health and Welfare, 137-1 Enokizu, Okawa-shi, Fukuoka 831-8501, Japan.
⁴ Systematic Review Workshop Peer Support Group (SRWS-PSG), Japan; Department of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan; Department of Nephrology and Dialysis, Kyoritsu Hospital, 16-5 Chuo-cho, Kawanishi, Hyogo 666-0016, Japan.
⁵ Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Abstract

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This study investigated the difference between COVID-19 RCT in medRxiv and in PubMed.
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SPIN in the conclusion was more frequently seen in reports in medRxiv than PubMed.
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Readers should pay attention to the overstatements in preprints of COVID-19 RCT.