Low-cost and versatile electrodes for extracellular chronic recordings in rodents

Heliyon. 2020 Sep 14;6(9):e04867. doi: 10.1016/j.heliyon.2020.e04867. eCollection 2020 Sep.


Electrophysiological data are used to investigate fundamental properties of brain function, its relation to cognition, and its dysfunction in diseases. The development of reliable and open-source systems for electrophysiological data acquisition is decreasing the total cost of constructing and operating an electrophysiology laboratory, and facilitates low-cost methods to extract and analyze the data (Siegle et al., 2017). Here we detail our method of building custom-designed low-cost electrodes. These electrodes can be customized and manufactured by any researcher to address a broad set of research questions, further decreasing the final cost of an implanted animal. Finally, we present data showing such an electrode has a good signal quality to record LFP.

Keywords: Behavioral neuroscience; Biological sciences; Electrodes; Electrophysiology; Local field potential; Low-cost; Neuroscience; Open-source; Systems neuroscience.