New surveillance guidelines for Li-Fraumeni and hereditary TP53 related cancer syndrome: implications for germline TP53 testing in breast cancer

Fam Cancer. 2021 Jan;20(1):1-7. doi: 10.1007/s10689-020-00207-z.
No abstract available

Keywords: Breast cancer; Heritable TP53-related cancer; Li-fraumeni syndrome; MRI; Penetrance; Sarcoma; TP53; Variant.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Alleles
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / therapy
  • Female
  • Gene Frequency
  • Genes, p53*
  • Genetic Testing / methods
  • Germ-Line Mutation*
  • Guidelines as Topic
  • Humans
  • Li-Fraumeni Syndrome / diagnosis
  • Li-Fraumeni Syndrome / genetics*
  • Li-Fraumeni Syndrome / therapy
  • Population Surveillance
  • Young Adult

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