First In-Human Experience With Inhaled Acetylsalicylic Acid for Immediate Platelet Inhibition: Comparison With Chewed and Swallowed Acetylsalicylic Acid

Circulation. 2020 Sep 29;142(13):1305-1307. doi: 10.1161/CIRCULATIONAHA.120.047477. Epub 2020 Sep 28.

Authors

Paul A Gurbel¹, Kevin P Bliden¹, Rahul Chaudhary², Udaya S Tantry¹

Affiliations

¹ Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, MD (P.A.G., K.P.B., U.S.T.).
² Division of Hospital Internal Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN (R.C.).

PMID: 32986482
DOI: 10.1161/CIRCULATIONAHA.120.047477

No abstract available

Keywords: aspirin; blood platelets; platelet aggregation.

Publication types

Clinical Trial, Phase I
Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Administration, Inhalation
Aged
Aspirin* / administration & dosage
Aspirin* / pharmacokinetics
Female
Humans
Male
Mastication
Middle Aged
Myocardial Infarction* / blood
Myocardial Infarction* / drug therapy
Platelet Aggregation Inhibitors* / administration & dosage
Platelet Aggregation Inhibitors* / pharmacokinetics

Substances

Platelet Aggregation Inhibitors
Aspirin