Considerations for the Selection and Use of Disinfectants Against SARS-CoV-2 in a Health Care Setting

Open Forum Infect Dis. 2020 Aug 31;7(9):ofaa396. doi: 10.1093/ofid/ofaa396. eCollection 2020 Sep.


Proper disinfection using adequate disinfecting agents will be necessary for infection control strategies against coronavirus disease 2019 (COVID-19). However, limited guidance exists on effective surface disinfectants or best practices for their use against severe acute respiratory coronavirus 2. We outlined a process of fully characterizing over 350 products on the Environmental Protection Agency List N, including pH, method of delivery, indication for equipment sterilization, and purchase availability. We then developed a streamlined set of guidelines to help rapidly evaluate and select suitable disinfectants from List N, including practicality, efficacy, safety, and cost/availability. This resource guides the evaluation of ideal disinfectants amidst practical considerations posed by the COVID-19 pandemic.

Keywords: COVID-19; EPA; List N; disinfectant; infection control; surface disinfection.