An eight-year-old girl with tracheal mass treated as a difficult asthma case

J Asthma. 2021 Dec;58(12):1689-1693. doi: 10.1080/02770903.2020.1825730. Epub 2020 Sep 29.

Abstract

Introduction: Endobronchial masses such as mucoepidermoid carcinomas or carcinoid tumors are extremely rare in children and they usually originate from large bronchi. These lesions may cause wheezing and dyspnea with poor response to bronchodilators and mimic the airway obstruction caused by asthma.

Case study: We present the case of an 8-year-old girl with tracheal mucoepidermoid carcinoma who was treated as a difficult asthma case with high dose of inhaled corticosteroids.

Results: The characteristic stridor, the lack of response to bronchodilators and to inhaled corticosteroid treatment, combined with the characteristic flow loop in spirometry and the hyperinflation seen on the chest radiograph, all raised the clinical suspicion of a tracheal lesion and indicated the need for flexible bronchoscopy. The bronchoscopy revealed a large lesion obstructing totally the trachea lumen. The latter finding was confirmed by chest high resolution CT. The mass was completely excised via sternotomy under cardiopulmonary bypass, and the pathologic examination showed a low-grade mucoepidermoid carcinoma of the trachea. One month after the surgery she was free of symptoms and her spirometry was normal.

Conclusion: Tracheal lesions mimic the symptoms of airway obstruction caused by asthma and should be always be part of the differential diagnosis in young patients with no response to asthma treatment.

Keywords: Case reports; control/management.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Adrenal Cortex Hormones / therapeutic use
  • Airway Obstruction
  • Asthma / diagnosis
  • Asthma / drug therapy
  • Carcinoma, Mucoepidermoid / diagnosis*
  • Carcinoma, Mucoepidermoid / diagnostic imaging
  • Carcinoma, Mucoepidermoid / pathology
  • Carcinoma, Mucoepidermoid / surgery
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Tracheal Neoplasms / diagnosis*
  • Tracheal Neoplasms / diagnostic imaging
  • Tracheal Neoplasms / pathology
  • Tracheal Neoplasms / surgery

Substances

  • Adrenal Cortex Hormones