Photo-controlled degradation of PLGA/Ti 3 C 2 hybrid coating on Mg-Sr alloy using near infrared light

Bioact Mater. 2020 Sep 15;6(2):568-578. doi: 10.1016/j.bioactmat.2020.08.013. eCollection 2021 Feb.


A PLGA/Ti3C2 hybrid coating was successfully deposited on the surface of magnesium-strontium (Mg-Sr) alloys. Compared with the corrosion current density (i corr ) of the Mg-Sr alloy (7.13 × 10-5 A/cm2), the modified samples (Mg/PLGA/Ti3C2) was lower by approximately four orders of magnitude (7.65 × 10-9 A/cm2). After near infrared 808 nm laser irradiation, the i corr of the modified samples increased to 3.48 × 10-7 A/cm2. The mechanism is that the local hyperthermia induced the free volume expansion of PLGA, and the increase in intermolecular gap enhanced the penetration of electrolytes. Meanwhile, the cytotoxicity study showed that the hybrid coating endowed the Mg-Sr alloy with enhanced biocompatibility.

Keywords: Coating; Degradation; Magnesium; Photoresponsive; Ti3C2 Mxene.